LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway

Abstract Background Osteosarcoma is highly malignant.The migration, invasion, and chemoresistance contribute to poor prognosis of osteosarcoma.Research reported that endogenous bornavirus-like nucleoprotein 3 pseudogene (EBLN3P) promotes the progression of osteosarcoma.Methods In this study, the expression of EBLN3P in osteosarcoma tissue with diff

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The Differential Antagonistic Ability of Curcumin against Cytotoxicity and Genotoxicity Induced by Distinct Heavy Metals

Widespread heavy metal pollution has aroused severe health risks worldwide.Curcumin has been reported to play a wide-spectrum protective role for various heavy metals.However, the specificity and difference in the antagonistic ability of curcumin against distinct types of heavy metals are still largely unknown.Here, using RINGS cadmium (Cd), arseni

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